For profparam, it’s used for fill peaks or align peaks instead of peak picking. It is the maximum allowed deviation between scans when locating regions of interest (ROIs), which is different from vendor number and you need to extend them larger than the company claimed. Centwave use a peak width range which should be checked on pool QC. prefilter with 3 and 100 means the ROI should contain 3 scan with intensity above 100. This algorithm use prefilter to accelerate the processing speed. When we find the ROIs, the peak shape is evaluated and ROI could be extended if needed. ROI means a region with stable mass for a certain time. The Centwave algorithm ( Tautenhahn, Böttcher, and Neumann 2008) based on detection of regions of interest(ROI) and the following Continuous Wavelet Transform (CWT) is preferred for high-resolution mass spectrum. 9.6 Method to validate the normalization.7.8.1 Chromatographic retention-related criteria.5.1 Platform for metabolomics data analysis.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |